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Paediatric Pulmonology and Allergology
2005 October, Vol. VIII, No. 2 (3019-3022)
BABY OF MOTHER WITH GENERALISED TUBERCULOSIS (CASE REPORT)
Elena Suciliene1, Danute Budgeniene1, Arunas Valiulis2, Iraida Bardiseviciene1, Nijole Drazdiene3, Ramute Vaitkeviciene3, Albina Nasliuniene3, Edvardas Zurauskas4
1 Vilnius University TB and Infection Diseases Hospital
2 Vilnius University Children’s Hospital, Center of General and Ambulatory Pediatrics
3 Vilnius University Children’s Hospital, Center of Neonatology
4 Lithuanian State Center of Pathology, Vilnius, Lithuania
A pregnant woman suffered from generalized tuberculosis (disseminated pulmonary tuberculosis with positive sputum smear, meningoencephalitis, tuberculosis of placenta). Newborn girl was born at 32 week of gestation with no clinical signs of tuberculosis. To prevent congenital tuberculosis in a face of unknown drug resistance of M. tuberculosis the treatment with isoniazid 10 mg/kg and rifampicin 10 mg/kg was initiated. In the serum of newborn antituberculosis IgG antibodies declined from 140 U/ml (normal value 120 U/ml) at birth till 75 U/ml at age of 80 days when her tuberculin skin test was negative and chest X-ray was normal. Treatment was stopped and BCG vaccination recommended. The level of antituberculosis antibodies helped to evaluate the status of baby. Treatment with antituberculosis drugs prevented the congenital tuberculosis.