Paediatric Pulmonology and Allergology

2003 October, Vol. VI, No. 2 (pp.2232-2235)

Diagnostic importance of immunoglobulins G, M, A in children with atopic dermatitis

Odilija Rudzeviciene, Irena Narkeviciute, Rimantas Eidukevicius

The aim of this stu­dy was to es­tab­lish the im­por­tan­ce of se­rum im­mu­nog­lo­bu­lins G, M, A in the diag­no­sis of ato­pic der­ma­ti­tis and the fre­qu­en­cy of lac­to­se ma­lab­sorp­tion in ato­pic der­ma­ti­tis chil­dren with nor­mal and chan­ged le­vels of the­se im­mu­nog­lo­bu­lins. We exa­mi­ned 76 chil­dren aged 1.5-23 months: 47 chil­dren with ato­pic der­ma­ti­tis (stu­dy group) and 29 no­nal­ler­gic chil­dren (con­trol group). Se­rum IgG, IgM, IgA we­re de­ter­mi­ned, lac­to­se and glu­co­se-ga­lac­to­se ab­sorp­tion tests we­re per­for­med. The nor­mal, inc­re­a­sed or dec­re­a­sed IgG, IgM, IgA blo­od se­rum le­vels in the stu­dy and con­trol group chil­dren sho­wed no sta­tis­ti­cal­ly sig­ni­fi­cant dif­fe­ren­ces, so it is no ne­ed to de­ter­mi­ne the­se im­mu­nog­lo­bu­lins in ato­pic der­ma­ti­tis chil­dren. In chil­dren with both nor­mal and al­te­red (inc­re­a­sed or dec­re­a­sed) IgG, IgM, IgA blo­od se­rum le­vels fre­qu­en­cy of lac­to­se ma­lab­sorp­tion was si­mi­lar.

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